Manuel Domínguez-Rodrigo is a Visiting Professor of Anthropology at Rice. His research focus is paleoanthropology and the archaeology of human origins, with methodological expertise in zooarchaeology, vertebrate taphonomy, and the application of artificial intelligence tools to paleoanthropology. He co-directs the Institute of Evolution in Africa (IDEA, Madrid, Spain) and is Professor of Prehistory at the University of Alcalá in Spain.

Since the 1990s, he has co-directed multiple paleoanthropological and archaeological projects in Tanzania, including at Peninj (Lake Natron), Lake Eyasi, and, currently, Olduvai Gorge, where he co-directs TOPPP (The Olduvai Paleoanthropology and Paleoecology Project). He has also conducted research at the paleoanthropological sites of Gona (Ethiopia). He has been a visiting scholar and visiting professor at Harvard University, Rutgers University, and University of Missouri at St. Louis.