The Aiden Lab explores all aspects of genome structure - from the 1D sequence of the bases to the 3D folding that enables them to fit inside the nucleus of a cell. Our 3D genome sequencing project probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing. We are interested in identifying genomic loci that are spatially co-located in vivo, including regions of intrachromosomal interactions and/or interchromosomal interactions, using techniques that may be applied to many different scales of interest. Several of our most recent projects have applied the study of genome assembly and architecture to inheritance and evolution within distinct species.
WEBSITE(S)| Aiden Lab | Google Scholar Publication List
Research Areas
Integrating mathematical and physical theory with the invention of new technologies with a central focus on the study of how genomes fold
Education
PhD, Applied Mathematics, Harvard University (2010)
PhD, Bioengineering, MIT (2010)
AB, Mathematics, Princeton University (2002)